Process Dev Engineering Scientist

Job Description General Summary Vertex is seeking a talented and motivated Scientist to join our Process Development team. The Process Development Engineering Scientist will lead projects focused on process development, optimization, and characterization of cell therapy products for current and future programs. This role involves hands-on work with large-scale bioreactors (50L and above) and will focus on developing scalable media and bioreactor processes to advance our Type 1 Diabetes program. Key Responsibilities Design and execute experiments to develop robust manufacturing processes for cell therapy products and support programs in clinical development. Develop robust, scalable media and bioreactor processes for cell therapy manufacturing. Evaluate novel and emerging technologies to advance project strategies. Lead projects within the team and provide training and support to scientists and engineers in large-scale bioprocessing and media scale-up. Apply deep knowledge of cell culture, bioreactor operations, and scale-up principles to process development activities. Use scientific and engineering fundamentals to support process design, development, and process understanding. Apply statistical tools and design of experiments (DOE) to guide process optimization. Develop process development and optimization strategies for 50L scale and beyond. Drive development activities in a cross-functional team environment. Author and review batch records, technical reports, and supporting documentation. Troubleshoot and resolve process challenges through the application of technical expertise and scientific judgment. Troubleshoot process and equipment-related issues and apply a strong understanding of large-scale bioprocessing equipment to support operations. Knowledge and Skills Experience in large-scale bioprocessing, including operation of 50L and above bioreactors. Strong understanding of large-scale bioprocessing equipment and demonstrated ability to troubleshoot equipment and process issues. Strong background in design of experiments (DOE) and statistical analysis. Strong understanding of cell culture processes and bioreactor scale-up. Excellent verbal and written communication skills, with the ability to communicate complex technical and scientific information clearly. Ability to manage multiple priorities, meet timelines, and adapt in a fast-paced environment. Qualifications Bachelors degree in Chemical Engineering, Bioengineering, Biochemistry, Biology, or a related field with 68 years of relevant experience, or Masters degree with 46 years of relevant experience, or PhD with 03 years of relevant experience. Pay Range: $104,000 - $156,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortunes 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change peoples lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.