Facilities Maintenance Supervisor

Position Summary: The Facilities Maintenance Supervisor leads maintenance operations to ensure the safe, compliant, and highly reliable performance of critical manufacturing and facility systems supporting cell therapy production in Tarzana, CA. In a Cell Therapy environment, where products are often patient-specific and time-sensitive, this role is critical to maintaining uninterrupted operations, cleanroom conditions, and strict chain-of-identity and chain-of-custody controls Tarzana, CA. The role integrates reliability engineering principles with daily maintenance execution, focusing on eliminating repeat failures, reducing unplanned downtime, and improving asset lifecycle performance in a highly regulated environment governed by FDA expectations and advanced therapies guidelines. Success in this role requires the ability to: Lead teams in a fast paced, patient-centric manufacturing environment Balance speed, compliance, and precision Anticipate and mitigate risks to critical, often irreplaceable batches Drive transition from reactive to predictive maintenance strategies Collaborate multi-functionally with Manufacturing, Quality, and Engineering to support 7 days cell therapy operations Ultimately, the Maintenance Supervisor plays a direct role in ensuring that life-saving therapies reach patients safely, reliably, and on time, by maintaining the integrity and performance of the systems that produce them. Responsibilities: Leadership & Team Management: Manage and mentor maintenance technicians; set clear expectations for safety, quality, and performance; lead daily tier meetings and shift handovers; build a culture of ownership, urgency, and continuous improvement; collaborate with Engineering, Quality, and Operations. Maintenance Execution & Compliance: Ensure all activities meet GMP, FDA, and site standards; review and approve complete, accurate work orders; enforce CMMS usage (e.g., SAP); lead aspects of preventive and corrective maintenance and calibrations; maintain inspection readiness and support audits. Reliability & Asset Management: Implement reliabilitycentered maintenance; investigate failures using RCA and FMEA; improve MTBF and MTTR; identify and resolve bad actor equipment; partner on upgrades and lifecycle management. Planning & Scheduling: Work with the Maintenance Planner to prioritize and schedule work; secure parts, tools, and permits in advance; validate and refine job plans; increase labor efficiency and minimize reactive work. Safety, Health, and Environment (SHE): Enforce LOTO, confined space, and permit systems; conduct safety observations, audits, and incident investigations; lead by example to sustain a zeroincident culture. Continuous Improvement: Remove waste from maintenance processes; increase schedule compliance, PM efficiency, and spareparts management performance; lead or participate in Kaizen and Lean initiatives. Work Environment: AZ is a cGMP regulated pharmaceutical manufacturing facility. We require your presence on the production floor and occasional off-shift support This may involve gowning for cleanroom environments Minimum requirements: High school diploma/GED required. 8+ years in industrial facilities maintenance/leadership experience 4+ years of leadership experience in a pharmaceutical, biotech, or GMP regulated environment (medical device/food service may be acceptable.) Desirable: Technical diploma/apprenticeship in HVAC or Boiler maintenance. Bachelors degree in Mechanical engineering or Facilities Management is a plus. . The annual base salary for this position ranges from $89,874 to $134,812. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Our Benefits: Benefits offered include: A qualified retirement program [401(k) plan] Paid vacation, holidays, and paid leaves Health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. #celltherapy Date Posted 03-Apr-2026 Closing Date 19-Apr-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the worlds most serious diseases. But we are more than one of the worlds leading pharmaceutical companies. At AstraZeneca, were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. Were curious about science and the advancement of knowledge. We find creative ways to approach new challenges. Were driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, youll do work that has the potential to change your life and improve countless others. And, together with your team, youll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.