Staff Scientist

Department BSD MED - Genetic Medicine - Center for Chemical Biology and Therapeutics (CCBT) About the Department The Center for Chemical Biology and Therapeutics (CCBT) at the University of Chicago is newly established and dedicated to interdisciplinary and translational research that bridges chemical biology and clinical applications. Co-directed by Dr. Hening Lin and Dr. Chuan He, the Center fosters collaboration between chemists, biologists, engineers, and clinical scientists to advance drug discovery and therapeutic development. CCBT will organize monthly faculty meetings, symposiums, workshops, and students/postdoc seminars to enhance collaboration across different fields. The Center will also build a Therapeutic Core Facility to support drug discovery efforts. This staff scientist position will lead the chemical biology effort of the Therapeutic Core Facility. Job Summary The Staff Scientist will play a key role in supporting and advancing the research initiatives of CCBT. The ideal candidate will have expertise in chemical biology, protein biochemistry, protein structure determination, assay development, mammalian cell culture, and will contribute to experimental design, project execution, data analysis, and scientific communication. This position provides an excellent opportunity to work in a dynamic and collaborative research environment while driving innovative therapeutic discoveries. Responsibilities Lead the chemical biology efforts in the Therapeutic Core Facility. Design and perform experiments in areas such as protein expression, protein purification, structure determination, protein evolution, protein engineering, phage display, cell-based assays, and animal experiment. Collaborate with faculty, postdocs, and students to facilitate research programs. Provide technical expertise, mentorship, and training to junior researchers. Participate in grant writing, manuscript preparation, patent application, and scientific presentations. Oversee research operations, equipment maintenance, and laboratory protocols of the Therapeutic Core. Support the development of the Therapeutic Core Facility by optimizing workflows and methodologies. Coordinate with external partners, core facilities, and funding agencies as needed. Train and supervise non-PhD level lab technicians/assistants. Follow all research safety regulations and ensure that the Therapeutic Core Facility operates in a safe environment. Assist the Center Directors in areas as needed. Serves as a resource for collecting data and performing analysis. Facilitates and promotes a research project by providing scientific or intellectual information. Develops laboratory protocols and training on new techniques. Manage, analyze and make recommendations on complex data sets for research. Performs other related work as needed. Minimum Qualifications Education: Minimum requirements include a PhD in related field. Work Experience: Minimum requirements include knowledge and skills developed through 5-7 years of work experience in a related job discipline. Certifications: --- Preferred Qualifications Experience: Research experience in a related job discipline as evidenced by high-quality publications. Preferred Competencies Strong experimental and analytical skills in protein biochemistry. Proven track record of scientific publications and research contributions. Excellent written and verbal communication skills. Ability to work independently and collaboratively in a multidisciplinary environment. Strong manuscript and proposal writing skills. Ability to work with people from different backgrounds. Strong problem-solving skills. Application Documents Resume/CV (required) Cover Letter (required) When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application. Job Family Research Role Impact Individual Contributor Scheduled Weekly Hours 40 Drug Test Required No Health Screen Required No Motor Vehicle Record Inquiry Required No Pay Rate Type Salary FLSA Status Exempt Pay Range $80,000.00 - $100,000.00 The included pay rate or range represents the Universitys good faith estimate of the possible compensation offer for this role at the time of posting. Benefits Eligible Yes The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook. 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