Analytical Development Senior Research Associate

Job Description Vertex is seeking a talented scientist to join our Analytical Development group in Boston, MA. This individual will help advance transformative medicines treating the underlying cause of serious diseases by contributing to analytical chemistry activities for small molecule programs in early development (preclinical through Phase 1). Responsibilities include analytical support of process and formulation development activities, characterization and stability of drug substance and drug products, as well as contributing scientifically to the resolution of broader drug development challenges in collaboration with other R&D functions. The ideal candidate will have knowledge of laboratory techniques commonly used in the analysis of pharmaceuticals such as LC, GC, and KF. Key Duties and Responsibilities: Designs, executes, and interprets experiments, with a high degree of reliability and independence. Compiles results into conclusions or recommendations for discussions with manager Performs method development experiments (LC, GC, KF) in collaboration with Subject Matter Expert (SME) teams Designed and executes phase appropriate stability studies for drug substance and drug products Maintains accurate laboratory notebooks Presents results at internal Project Team research meetings Performs experimental troubleshooting Contributes collaboratively to team goals Knowledge/Skills: The ability to work successfully in a team/matrix environment The ability to work in a fast-paced environment, manage priorities, and maintain timelines for multiple projects Proven technical prociency and demonstrated skill in designing, executing and interpreting experiments. Uses own judgment to execute follow-up experiments, including troubleshooting Understanding of LC, KF, GC, and other techniques commonly used for pharmaceutical analysis and how they are applied. Fundamental understanding of method development and validation of these techniques Demonstrates understanding of own discipline and aspects of drug development regulations and compliance Demonstrates ability to provide high quality data collected in a compliant fashion in support of regulatory submissions and/or manufacturing Demonstrates effective, self-sufficient communication skills, especially in peer/team discussions Good written and verbal communication skills Education and Experience: Bachelor's degree (or equivalent degree) and 4+ years of experience in analytical development program or other analytical support function, or Master's degree (or equivalent degree) and 0-2 years of experience in analytical development program or other analytical support function Pay Range: $70,400 - $105,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortunes 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change peoples lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.