Senior Scientist, Cell Therapy Discovery

Senior Scientist, Cell Therapy Discovery Introduction to role Are you ready to dive into the world of Cellular Therapy and make a difference in patients' lives? We are on the lookout for a driven and independent Senior Scientist with a knack for Computational Biology applied to Cellular Therapy, Immunology, and Immuno-Oncology. Join our dynamic Cell Therapy Team and contribute to groundbreaking advancements by developing computational models, designing experiments, and interpreting scientific data. This role is based in Gaithersburg, MD, USA. Accountabilities Plan, conduct, and troubleshoot discovery research experiments independently. Assess and report data with a clear understanding of its implications within the overall context of drug discovery, independently formulate conclusions, and determine future experiments. Design, develop, and deploy AI-driven machine learning and deep learning models to extract knowledge and insights from structured and unstructured data sources relevant to the development of new therapies. Provide technical instruction to the team and allocate administrative work where possible. Work collaboratively in a matrix environment. Prepare and deliver presentations within the Cell Therapy Unit and across other functions. Ensure own work, and work of peers, are compliant with relevant internal AstraZeneca standards and external regulations. Essential Skills/Experience PhD in relevant disciplines or equivalent experience (e.g. Bioinformatics, Systems Biology, Applied Mathematics, Statistics, Data Science, Computer Science). Minimum of 3 years of experience in Cellular Therapy, Immunology, Immuno-Oncology, Computational Biology, and/or Data Science. Proficiency in Python and/or R. Prior experience in UNIX-based systems, high-performance computing (e.g. SLURM), and large-scale data management. Expertise in omics technologies, capable of processing large-scale biological datasets (e.g. single-cell/spatial transcriptomics, in-house proprietary data sources such as in vitro or in vivo data). Deep understanding of AI, predictive modelling, and statistical methods applied to training of machine learning models. Hands-on expertise in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, cytokine measurement, and multi-parameter flow cytometry. Ability and motivation to drive projects to completion in a team environment. Desirable Skills/Experience Experience in drug development in an industry setting. AstraZeneca offers an inspiring environment where your expertise can make a profound impact. With a commitment to continuous improvement and innovation, we embrace challenges and thrive on collaboration. Our dynamic approach ensures that every setback is an opportunity for growth. Here, you'll be part of a team that values curiosity and courage, pushing boundaries to deliver life-changing medicines to patients worldwide. At AstraZeneca, we seize opportunities to innovate and redefine whats possible in biopharmaceuticals. Our mission to deliver transformative medicines is underpinned by a culture of collaboration, inclusivity, and ambition. Join us in a role where your work directly gives to breakthroughs in oncology, empowering patients and changing lives. Ready to take the next step in your career? Apply now and be part of something extraordinary! The annual base pay (or hourly rate of compensation) for this position ranges from $108,473.60 to $162,710.40. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans Date Posted 29-Oct-2025 Closing Date 11-Nov-2025 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the worlds most serious diseases. But we are more than one of the worlds leading pharmaceutical companies. At AstraZeneca, were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. Were curious about science and the advancement of knowledge. We find creative ways to approach new challenges. Were driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, youll do work that has the potential to change your life and improve countless others. And, together with your team, youll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.