Job Description GENERAL POSITION SUMMARY: This individual will provide support to the Global Facilities Technologies department as part of the Reliability Engineering team. The Facilities Engineering Senior Specialist (Reliability Engineer) will have a lead role in the reliability engineering team for Vertex GMP and Non-GMP sites.. The Reliability Engineering Senior Specialist is responsible for driving continuous improvement initiatives, providing technical support and SME knowledge, performing Failure Mode and Effects Analysis (FMEA), Criticality Assessments, Equipment Trend Reports, and Root Cause Analysis (RCA) to minimize equipment failures and maximize equipment availability. In this role you will also be responsible for identifying potential risks to minimize equipment downtime and optimize equipment efficiency through maintenance best practice, analysis, and continuous improvement initiatives. This role will also be responsible for the creation, optimization, and implementation of preventive maintenance plans for all site equipment. This resource will collaborate with stakeholders from FacOps, Metrology, Engineering, Commissioning and Qualification, End users, Corporate Asset Management and Quality Assurance. This resource will use Good Engineering Practices as well as Maintenance and Reliability Best Practices to support operational readiness and continuous improvements across all Vertex sites. Key Responsibilities: Manage/Oversee site Reliability Engineering team. Lead the development, implementation, and continuous improvement of Reliability Engineering assessments. Drive continuous improvement of maintenance, calibration, and engineering service delivery, adopt, and deploy best practices across all Vertex sites. Perform and review spare parts assessments to determine critical spares and recommended stock levels to minimize the likelihood of unplanned part-related downtime. Help lead CMMS data specialist team for implementation of maintenance, calibration and spare parts improvements based on equipment trending, feedback to reliability and other continuous improvement initiatives/forums. Perform Root Cause Analysis on equipment to prevent future failures and reduce unplanned downtime. Conduct reliability assessments and analyses to identify potential failure modes and develop strategies for mitigation. Develop and advance Reliability Engineering KPI's to improve equipment reliability and decision making. Monitor equipment performance metrics to analyze data and predict potential failures. Identify equipment design improvements to minimize unplanned downtime and optimize cost effectiveness. Generate, manage, and maintain Reliability Engineering reports. Support global reliability/resiliency/sustainability initiatives from site level. Develop, grow, and advance the predictive maintenance programs. Minimum Qualifications: Bachelors degree in mechanical engineering or other relevant engineering discipline and 2-6 years of experience in Reliability Engineering, or comparable role. Aptitude for mechanical and electrical systems. How they operate, how they fail, ways to extend equipment reliability and life Strong people skills, including the demonstrated ability to manage through influence. Understanding and familiarity with Reliability Engineering best practices/methodologies and maintenance best practices. Experience in GxP or other similarly regulated environment with an understanding and application of technical principles, theories, and concepts in the field, GMP, ISO, GAMP, ANSI. Experience working in a Computerized Maintenance Management System. Ability to work in a team setting and foster collaboration across all departments. Proficiency in data analysis and KPI buildout. Pay Range: $102,200 - $153,300 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortunes 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change peoples lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.