Manufacturing Specialist

At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Position Summary We are seeking a Manufacturing Specialist to support our dynamic Manufacturing team in the production of autologous cell therapy investigational products. This role is based in Tarzana, CA. This role will report to the Associate Director of Manufacturing or Manufacturing Manager. The Specialist, Manufacturing role will ensure successful manufacture and release of cell therapy products by following established processes in full compliance with cGMP. This role also supports manufacturing operational readiness and the successful technology transfer of pipeline products using knowledge of cGMP regulations. Responsibilities Using general application of principles, support activities to ensure GMP readiness for clinical manufacturing, including equipment procurement, installation and qualification, facility qualification, and technology transfer. Perform tasks in a manner consistent with safety policies, quality systems, and cGMP requirements. Assist in developing Standard Operating Procedures (SOPs) for manufacturing processes. Set up manufacturing areas and equipment, including complex automated cell processing equipment. Follow all cleaning and gowning procedures for the facility. Maintain appropriate inventories of material and supplies within the cleanroom areas to support manufacturing activities. Ensure all materials and equipment are identified and available in time for manufacturing activities. Support Process Development to align manufacturing plans with product development plans. Ensure that all production operations are controlled and performed within cGMP regulatory guidelines. Provide verbal and written escalations to Manufacturing leads and manager, as appropriate. Perform other responsibilities and project-based assignments as needed to support manufacturing operations. Experience and Education Minimum of five (5) years of experience with a High School Diploma or a BS/BA in a relevant science or engineering discipline. Understanding of cGMP process and knowledge of CMC regulatory framework for biologics. Knowledge of aseptic techniques for primary human cell cultures and GMP manufacturing and supporting tech transfer and GMP clinical/commercial manufacturing operations. Additional Requirements Knowledge of industry practices, cell therapy manufacturing experience preferred. Develop solutions to complex problems independently. Refer to established precedents and policies or use original thinking. Help determine goals of assignment. Plan schedules and arranges own activities. Work is reviewed upon completion for adequacy in meeting goals. Be onsite 4 days a week to support a 10 hour shift The annual base pay (or hourly rate of compensation) for this position ranges from $81,992 to $122,989. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 25-Mar-2026 Closing Date 07-Apr-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the worlds most serious diseases. But we are more than one of the worlds leading pharmaceutical companies. At AstraZeneca, were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. Were curious about science and the advancement of knowledge. We find creative ways to approach new challenges. Were driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, youll do work that has the potential to change your life and improve countless others. And, together with your team, youll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.