Staff Engineer Agentic AI, Oncology Data Science & AI

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. In AstraZeneca Oncology, our goal is to be at the forefront of developing the next generation of cancer therapies. This Staff Engineer Agentic AI role is located in either Boston, MA, or Gaithersburg, MD Main Duties and Responsibilities There is an exciting opportunity for a talented and motivated Engineer to join the group as a Staff Engineer for Agentic AI. In this role, you will: Build Agentic AI driven solutions that tackle scientific research problems. Develop, test, and support Agentic tools for Genomics, Computational Pathology, Clinical Trials, etc. Automate complex data analysis processes. Introduce leading AI technologies applied to cancer research. Essential Requirements Relevant graduate degree: Computer Science, Engineering, or Bioinformatics. Minimum of 10 years of applied experience in software engineering, data science, machine learning, bioinformatics, or relevant field. Hands-on experience building Agentic AI systems and deploying them to production. Programming skills: Solid Python and/or TypeScript programming skills Vast Experience in: Unix, SQL databases, REST APIs, Cloud computing (AWS). Vast Experience in software development best practices. Desirable: AI frameworks, such as Pydantic-AI, LangChain, etc. Experience in RAG, vector databases. An understanding of LLMs / Foundation models technologies. Experience in at least one compiled programming language (e.g. any of C, Java, Go, Rust, etc.). The annual base pay for this position ranges from $177,520.00 - $266,280.00. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 10-Nov-2025 Closing Date 11-Dec-2025 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the worlds most serious diseases. But we are more than one of the worlds leading pharmaceutical companies. At AstraZeneca, were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. Were curious about science and the advancement of knowledge. We find creative ways to approach new challenges. Were driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, youll do work that has the potential to change your life and improve countless others. And, together with your team, youll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.