Ex Vivo Neuroscientist

Band Level 3 Job Description Summary The Neuroscience Disease Area within Biomedical Research at Novartis is a global research organization striving to develop impactful medicines for people living with severe neurological diseases. We are seeking a highly motivated scientist to join the Neuroscience DA in Cambridge, Massachusetts. This hands-on position will be to support project teams working on new therapies for neurodegeneration indications through the development of ex vivo models and evaluation of functional endpoints via electrophysiological and immunohistochemical studies. The successful candidate will interact with cross-functional project teams and therefore teamwork and good communication skills are key. Job Description #LI-Onsite Site: Cambridge, MA The Neuroscience Disease Area within Biomedical Research at Novartis is a global research organization striving to develop impactful medicines for people living with severe neurological diseases. We are seeking a highly motivated scientist to join the Neuroscience DA in Cambridge, Massachusetts. This hands-on position will be to support project teams working on new therapies for neurodegeneration indications through the development of ex vivo models and evaluation of functional endpoints via electrophysiological and immunohistochemical studies. The successful candidate will interact with cross-functional project teams and therefore teamwork and good communication skills are key. Key Responsibilities: Hands-on execution of cellular and network electrophysiological studies in cell culture and/or in brain slices to characterize molecules for potential therapeutic effects. Immunohistochemical analysis of protein expression in brain slices Optimization of experimental protocols for evaluation of functional measures Analyze, interpret data and present summary to project teams Write experimental protocols and record experiments in electronic notebook Present results in unit and department meetings Strong teamwork skills and a good lab partner Essential Requirements: A minimum of a Bachelors degree in Neuroscience or related discipline and a minimum of 4+ years of laboratory-based industrial or academic experience Hands-on experience working with rodents Familiarity with in vitro/ex vivo electrophysiology i.e. whole cell patch clamp, high throughput electrophysiology platforms, or extracellular field potential recordings Experience with immunohistochemistry or immunocytochemistry Interest in troubleshooting data anomalies to maintain high data quality Patience and attention to detail are essential Interest in learning about brain diseases, drug targets and new techniques Experience with statistical analyses and application to biological data Proficiency with Microsoft Office (Outlook, Excel and PowerPoint) Flexibility and willingness to occasionally adjust working hours as required by specific experiments Preferred Qualifications: Priority will be given to candidates with experience in acute brain slice electrophysiology Familiarity with scientific/analytical software packages/platforms (e.g. IGOR Pro, Fiji, Graphpad, MATLAB, Python, R). Programming experience is a plus. The salary for this position is expected to range between $85,000 and $158,000 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. https://www.novartis.com/careers/careers-research/notice-all-applicants-us-job-openings Salary Range $85,400.00 - $158,600.00 Skills Desired Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication Skills, Curiosity, Data, Data Analysis, Design Of Experiments, Detail-Oriented, Diversity & Inclusion, Drug Discovery, Ethics, Gene Therapy, Immunology, Laboratory, Lifesciences, Machine Learning (Ml), Mammalian Cell Culture, Medical Research, Molecular Biology {+ 11 more} Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing peoples lives. 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