Bioinformaticist - Psychiatry

Scheduled Hours 40 Position Summary The NeuroGenomics and Informatics (NGI) group at WashU Medicine is recruiting a Human Statistical Genomicist to work in Dr. Cruchagas lab at the WashU Medicine. The NGI holds whole exome and genome sequencing data from over 10,000 subjects that is locally generated or from public repositories. At the NGI we are constantly growing our dataset and generating new data-freezes; as such we are constantly improving and updating our pipelines to keep up with advances in the field. We are seeking a talented and motivated employee to make important contributions to the study of the genetics of Alzheimer Disease and related dementias. This position will work directly with the head of the Genomics Unit at the NGI to organize, develop, implement, and manage genome sequencing data pipelines that will be used in downstream analysis and projects. They will join a team of computational and statistical researchers working in bioinformatics, statistical genomics, and genetics. The team comprises over 20 people dedicated to understanding the architecture of neurodegenerative diseases. Job Description Primary Duties & Responsibilities: Revise and improve existing WES and WGS data processing and analysis pipelines, including QC, data organization, and back up. Consistently improve pipelines as datasets/requirements change and adapt to new computational environments. Provide advice on data processing and analysis to other team members. Assist other team members in receiving and sharing data from collaborators. Manage, teach, and supervise junior scientists in processing sequencing data. Participate in meetings within the group and with other institutions and investigators. Assist in manuscript, grant, and report writing sections such as materials and methods and results. Experience handling hundreds-to-thousands of samples at once from different batches and how to deal with potential derived artifacts, and expertise with BWA-MEM, GTAK. Experience with analysis tools such as PLINK, SKAT, SKAT-O, METAL, rare-METAL and other gene burden tools, Advanced knowledge of Unix-based operating systems. Proficient in computing skills and knowledge of R, Python, and/or similar scripting languages is essential. Experience using common software (Excel, R, ggplot, PowerPoint, etc.) for preparing and presenting reports, figures, and graphic data representations. Working Conditions: Job Location/Working Conditions Normal office environment Physical Effort Typically sitting at a desk or table Equipment Office equipment The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time. Required Qualifications Education: Bachelor's degree Certifications: No specific certification is required for this position. Work Experience: Research (4 Years) Skills: Not Applicable Driver's License: A driver's license is not required for this position. More About This Job For more information about the NeuroGenomics and Informatics group, please visit their website at the following link. Preferred Qualifications: Experience processing and analyzing whole exome and whole genome sequencing data in the area of human genetics. Preferred Qualifications Education: Master's degree - Human And Statistical Genetics Certifications: No additional certification unless stated elsewhere in the job posting. Work Experience: Bioinformatics Or Related Discipline (4 Years) Skills: Ability to Reason, Analytical Thinking, Big Data Processing, Bioinformatics, Bioinformatics Tools, Biostatistics, Communication, Complex Data Analysis, Computational Biology, Data Management, Data Presentations, Discrete Mathematics, Genome Sequencing, Ggplot, Human Genomics, Machine Learning, Microsoft Office, Perl Programming, PLINK (Software), Probabilistic Modeling, Python (Programming Language), Statistics, System Administration Grade R11 Salary Range $55,200.00 - $100,000.00 / Annually The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget. Questions For frequently asked questions about the application process, please refer to our External Applicant FAQ. Accommodation If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship. Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. Benefits Statement Personal Up to 22 days of vacation, 10 recognized holidays, and sick time. Competitive health insurance packages with priority appointments and lower copays/coinsurance. Take advantage of our free Metro transit U-Pass for eligible employees. WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%. Wellness Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more! Family We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? Weve got you covered. WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us. For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/ EEO Statement Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the Universitys policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. Washington University is dedicated to building a community of individuals who are committed to contributing to an inclusive environment fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply. Should I consider applying to older job postings? Yes. Due to the unique needs of each search, the selection process may occur at different paces for open positions. Individuals are encouraged to apply to all open positions of interest for which they meet the Required Qualifications. Washington University in St. Louis' collective success is significantly attributed to the passion and outstanding efforts of our community. Our staff, faculty and trainees are committed to excellence and dedicated to carrying out our missions of research, teaching and patient care. WashU prides itself on being a place where people matter, and serious work is done. Our people work together in an inclusive community that celebrates diverse perspectives, collaboration and innovation. We are a community of individuals inspired to work together to develop big ideas and tackle challenging problems. We value the well-being of our people. WashU strives to create a positive employee experience where staff, faculty and trainees thrive, both personally and professionally. Our employees find meaning, connection and vitality in their work and life with a healthy work-life balance and support to learn, grow and make an impact at WashU, the community and the world. Useful Links Who We Are Human Resources Benefits Living in St. Louis Frequently Asked Questions Accommodation If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. 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